Kell K/k (KEL) Antigen Genotyping, Fetal
Ordering Recommendation
Fetal Kell (K/k) genotyping to assess risk for alloimmune hemolytic disease. For parental or neonatal testing, refer to Kell K/k (KEL) Antigen Genotyping (3002001).
New York DOH Approval Status
Specimen Required
Amniotic fluid
OR cultured amniocytes OR cultured CVS: Two T-25 flasks at 80 percent confluency.
AND whole blood for maternal cell contamination: lavender (EDTA), pink (K2EDTA), yellow (ACD solution A or B).
If the client is unable to culture, order test Cytogenetics Grow and Send (ARUP test code 0040182) in addition to this test and ARUP will culture upon receipt (culturing fees will apply). If you have any questions, contact ARUP's Genetics Processing at 800-522-2787 ext. 3301.
Amniotic fluid: Transport 10 mL amniotic fluid in a sterile container (Min: 5 mL) OR cultured amniocytes OR cultured CVS: Fill flasks with culture media. Backup cultures must be retained at the client's institution until testing is complete.
Whole blood for maternal cell contamination: Transport 3 mL whole blood (Min: 1 mL)
Amniotic fluid, cultured amniocytes, or cultured CVS: CRITICAL TEMPERATURE. Must be received within 48 hours of shipment due to lability of cells.
Whole blood for maternal cell contamination: Refrigerated.
Frozen specimens in glass collection tubes.
The Patient History Form is available on the ARUP website or by contacting ARUP Client Services.
Fetal specimens: Ambient: 48 hours; Refrigerated: 48 hours; Frozen: Unacceptable
Whole blood for maternal cell contamination: Ambient: 72 hours; Refrigerated: 1 week; Frozen: 1 month
Methodology
Polymerase Chain Reaction (PCR)/Fluorescence Monitoring/Fragment Analysis
Performed
Varies
Reported
3-10 days
Reference Interval
By report.
Interpretive Data
Refer to report.
Modified FDA
Note
Hotline History
Hotline History
CPT Codes
0001U; 81265 Fetal Cell Contamination (FCC)
Components
Component Test Code* | Component Chart Name | LOINC |
---|---|---|
0050548 | Maternal Contamination Study Fetal Spec | 59266-7 |
0050612 | Maternal Contam Study, Maternal Spec | 66746-9 |
3016677 | KEL Genotype, Fetal Specimen | |
3016678 | KEL Genotype Fetal, Interpretation |
Aliases
- KEL1 and KEL2 genotyping
- Kel1 heterozygosity or homozygosity assay
- Kell Antigen genotyping
- Kell/Cellano genotyping